# Shifting the Balance Towards Social Interventions:

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## Shifting the Balance Towards Social Interventions:

## A Call for an Overhaul of the Mental Health System

### Beyond Pills All-Party Parliamentary Group

May 2024

This is not an official publication of the House of Commons or the House of Lords. It has not been approved by either House

or its committees. All-Party Parliamentary Groups are informal groups of Members of both Houses with a common interest

in particular issues. The views expressed in this report are those of the group.

Preface .......................................................................................................................................3

Executive summary ....................................................................................................................5

Why we need an overhaul of our mental health system ..........................................................7

The WHO/UN call for mental health reform .............................................................................9

Six principles for mental health reform...................................................................................13

1. Mental health problems are mostly about our circumstances and relationships.........13

2. Mental health problems arise within our social environments.....................................13

3. Mental health problems are exacerbated by societal messages...................................14

4. Positive narratives and language are needed for recovery ...........................................14

5. Psychiatric drugs should be used with caution and over-prescribing reduced .............14

6. Research should focus on better psychosocial provision ..............................................15

Calls for action .........................................................................................................................16

Services ................................................................................................................................16

1. Boost provision for social interventions, including social prescribing and

community-based resources ...........................................................................................16

2. Fund and deliver community-based mental health hubs for people of all ages.....17

3. Fund and deliver a national 24-hour prescribed drug withdrawal helpline and

website.............................................................................................................................18

4. Reverse the rate of unnecessary antidepressant prescribing .................................19

Regulation ............................................................................................................................20

5. Reform the MHRA, the regulator of medicines in the UK .......................................20

6. Implement a UK Sunshine Act to improve transparency of financial conflicts of

interest.............................................................................................................................21

Education and training.........................................................................................................21

7. Integrate Social Emotional Learning (SEL) into the national curriculum.................21

8. Improve the education and training of health professionals ..................................23

Public and professional awareness......................................................................................24

9. De-medicalise mental health language in both public and professional spaces.....24

Conclusion................................................................................................................................27

### Preface

This report points the way to a higher quality and more effective approach to mental health,

which will improve the lives of millions of people and strengthen the UK economy. Its

recommendations align with recent calls from the World Health Organisation and the

United Nations for systematic mental health reform.

The report begins by describing the current mental health crisis, which affects around a

quarter of adults and children in the UK and has enormous individual, societal and economic

costs. This is happening despite increased investment in traditional approaches to mental

health. These existing approaches are simply not working.

Shifting the Balance Towards Social Interventions calls for radical change with a shift

towards more social interventions and away from pharmaceutical and other purely

biomedical ones. This may seem counterintuitive in a country accustomed to think about

mental illness as an individual problem requiring medical treatment. The report, however,

points to the evidence of the impact on individuals of toxic relationships, family dysfunction

and breakdown, abuse, bullying, violence and other traumatic events and to the role of

wider societal factors such as economic insecurity, poverty, poor housing, inadequate

nutrition, and damaged communities. It goes on to set out six principles for mental health

reform.

The emphasis throughout is to move away from focusing purely on health services aimed at

treating individuals to concentrate much more on prevention through tackling the wider

causes of mental ill-health and, as importantly, on creating health by providing the

conditions for people to be healthy and, where appropriate, helping them to be so.

Implementation will be difficult. It requires major changes in clinical practice and

professional training as well as shifts in public perceptions. Equally importantly, as the

report describes so well, pharmaceutical companies have had far too much influence and

have benefitted accordingly. Medicines will still be needed for some patients, but the

existing levels of over-prescribing must be tackled.

The report proposes nine practical calls to action relevant to the mission of the Beyond Pills

APPG - some of which can bring immediate benefits as well as others that will take a great

deal of time and effort. Many clinicians recognise the need for these radical changes, but

they will need the leadership and support of the NHS, government and the professional

bodies.

I congratulate the authors of this report and commend it wholeheartedly. These are timely

and important recommendations.

Lord Nigel Crisp

Co-Chair of the Beyond Pills All-Party Parliamentary Group

Chief Executive of the English NHS and Permanent Secretary of the Department of Health

2000-2006

May 2024

### Executive summary

This report calls for urgent reform of the mental health sector in the United Kingdom.

It highlights the pressing need to address the current crisis in mental health outcomes,

which is characterised by high rates of psychiatric drug prescriptions, lengthy waiting times

for treatment, soaring societal and individual costs of worsening mental health, and

persistently poor outcomes despite significant investments in services and research over the

past four decades.

Key findings of the report include:

1. Mental health outcomes have not improved despite substantial investments in

services and research, with rates of poor mental health worsening in the general

population and the mortality gap widening between individuals with severe mental

health problems and the general population.

2. The dominant biomedical model of mental health care has led to over-reliance on

psychiatric drugs and neglect of effective social, community and relational

approaches. This approach fails to address the underlying social, economic and

psychological determinants of mental distress and is contributing to worsening

outcomes.

3. The United Nations and WHO have called for fundamental reforms in mental health

care, emphasising the importance of psychological and social support alongside

efforts to address the social causes of distress.

4. The report outlines six principles for mental health reform, including recognising the

social and relational nature of mental health problems, addressing the social

determinants of distress, challenging societal messages that contribute to emotional

distress, promoting positive narratives and language to support recovery, using

psychiatric drugs with caution, and prioritising research on psychosocial

interventions.

In conclusion, the report emphasises the need for a paradigm shift in mental health care

towards a more holistic and person-centred approach that addresses the social, economic

and psychological factors contributing to mental distress. Facilitating this shift is not the sole

responsibility of government; it requires everyone involved in the UK mental health system

to play an active part.

The Beyond Pills APPG has identified nine specific recommendations relevant to its mission

that it will be advocating for in the following arenas as its contribution to this shift:

### Services

1. Boost provision for social interventions including social prescribing

2. Fund community-based mental health hubs for all ages

3. Fund drug deprescribing services as well as a national withdrawal support helpline

4. Reverse rates of unnecessary antidepressant prescribing

### Regulation

5. Reform the MHRA, the regulator of medicines in the UK

6. Implement a UK Sunshine Act to improve transparency of conflicts of interest in

medicine

### Education

7. Integrate Social and Emotional Learning programmes within the national curriculum

8. Improve the education and training of health professionals

### Public and professional awareness

9. De-medicalise mental health language

By adopting the recommended principles and supporting the needed reforms government

can improve mental health outcomes, reduce the rising economic burden of poor mental

health and promote overall societal health and well-being.

### Why we need an overhaul of our mental health system

We have reached a crisis point in the nation’s mental health. Nearly a quarter of the adult

population is prescribed a psychiatric drug in any given year,¹ and a similar proportion of

young people now meet the criteria for a mental health diagnosis.² Waiting lists for NHS

treatment are up to three years,³ NHS provision for psychotherapy is patchy and often of

low quality,⁴ and interventions directed at the social and psychological causes of distress

have been under prioritised.

According to the NHS Independent Mental Health Taskforce, mental health outcomes have

worsened in recent years, coinciding with an increase in rates of suicide.⁵ Indeed, taking a

longer view and looking at trends in mental health outcomes, they have at best flatlined

over the past four decades and according to some measures have deteriorated.⁶

For instance, despite efforts to broaden access to mental health services, there has been no

observable reduction in the prevalence of mental disorders since the 1980s,⁷ while mental

health disability has almost trebled in recent decades.⁸ Moreover, despite decades of work

and investment, current psychiatric drugs show no discernible superiority in overall efficacy

compared to the initial agents introduced over 50 years ago.⁹ While society has witnessed

remarkable gains in life expectancy over the last five decades, largely attributed to

biomedical advances in general medicine, individuals diagnosed with severe mental health

problems have not experienced commensurate improvements. Rather, the gap in life

expectancy between individuals with severe mental health issues and the general

population has doubled since the 1980s.¹⁰ Alarmingly, the mortality rate among individuals

experiencing severe and sustained emotional distress is now 3.6 times higher than that of

the general population, resulting in a significant reduction in life expectancy, with those

people who have been diagnosed dying approximately 20 years earlier than the average

person.¹¹ Such lack of progress in outcomes is a matter of significant concern given the

substantial resources (we estimate nearly a quarter of a trillion pounds) allocated to mental

health services, initiatives and research over the last four decades.

The failure of the mental health sector to achieve meaningful improvements in outcomes

has also resulted in an exacerbation of the economic burden of poor mental health on wider

society. A recent study commissioned by the NHS Confederation’s Mental Health Network

found that the total cost of poor mental health in England in 2022 alone was approximately

£300 billion.¹² The three major costs comprised:

1. Losses to the economy due to absenteeism and presenteeism at work, staff turnover

and unemployment among people with mental ill health: £110bn

2. The human costs of reduced quality of life and premature mortality: £130bn

3. The health and social care costs provided by public services and informal care

provided by family and friends: £60bn

For many within the mental health sector, the response to this crisis in outcomes, rising

costs and worsening mental health has been to call for more funding of conventional,

medicalised approaches as if ‘doing more of the same’ will lead to different results. The

evidence, however, suggests that our mental health crisis is not only a resource problem,

but a problem of having adopted the wrong approach: of having side-lined effective social,

community and relational approaches. We need to move from a system that has

significantly over-medicalised and mis-treated real mental distress (one that essentially

focuses on ‘symptom management’) to one that identifies and challenges the psycho-social

causes to which so much distress is a rational and understandable response. We need a

radical new vision of how best to frame and manage poor mental health in order to improve

clinical outcomes and reduce the escalating economic, societal and human burden of rising

levels of mental distress.

### The WHO/UN call for mental health reform

In 2017, two reports were published by the United Nations calling for greater attention to

be paid to the psychosocial drivers of mental distress in order to address the failure of our

mental health sectors to improve clinical outcomes.¹³ These reports built on a growing

consensus that, in most cases, mental health problems are understandable responses to life

circumstances - social, relational and psychological adversities that result in emotional

harms - and are not essentially medical problems to be solved by strictly medical

interventions.¹⁴ In other words, outcomes are failing due to the over-reliance of services on

the biomedical model¹⁵ - a model which misrepresents the nature and causes of much

mental distress and which systematically downplays the importance of psychosocial and

economic causes and solutions.

The World Health Organisation, in a recent report, broadly supported the UN’s critical

observations, urging us to pay greater attention to the social determinants of mental

distress, which it defines as “the conditions in which people are born, grow, live, work, and

age, and the wider set of forces and systems shaping the conditions of daily life…forces and

systems [that] include economic policies and systems, development agendas, social norms,

social policies, and political systems.” These forces and systems, as the WHO also indicates,

“are [in turn] shaped by the distribution of money, power and resources at global, national

and local levels, which are themselves influenced by policy choices.”¹⁶

Research into the situational and social determinants of poor mental health supports this

growing consensus (among the UN, WHO and beyond) about the importance of challenging

the social determinants of distress and has produced a vast body of evidence demonstrating

that poor mental health is inextricably linked to the contexts in which people live, work and

develop.

For example, there is now substantial evidence that the social conditions driving and

sustaining poor mental health are rooted in factors such as inequality,¹⁷ socioeconomic

disadvantage,¹⁸ unemployment,¹⁹ low socioeconomic status,²⁰ poor education,²¹ food

security,²² poor housing,²³ financial stress,²⁴ discrimination,²⁵ childhood adversity,²⁶

substance abuse,²⁷ family dysfunction and breakdown²⁸ as well as the breakdown of

community support and the inability to access effective and affordable mental health care.²⁹

Substantial evidence also shows that various forms of relational deprivation, such as early

trauma,³⁰ abusive family and other environments,³¹ neglect,³² loneliness,³³ bullying,³⁴ and

social media use³⁵ are key drivers of poor mental health.³⁶ Aside from such social and

relational drivers, poor mental health is also exacerbated by ineffective treatments,³⁷

iatrogenic or treatment harms,³⁸ as well as systematic underinvestment in psycho-social and

relational interventions.³⁹

The UN and WHO’s call to respond to the social determinants of distress, was further

supported in April 2024 by The BMJ Commission on the Future of the NHS, which launched a

report demanding urgent government action to tackle the social determinants of health in

order to reverse the deteriorating health and rising inequalities in the UK population.⁴⁰ It

called for leaders of all political parties to act on the evidence, starting by setting up a cross-

party task force accountable for public health in tandem with re-establishing Public Health

England. Priorities should include: implementing policies to tackle poverty so that people

can lead healthier lives; investing in sustainable housing compatible with good health; and

giving every child the best start in life. The report acknowledges that as adverse life

circumstances significantly affect mental health, a higher burden of population‐level mental

distress is disproportionately experienced by those closer to the margins of our societies.⁴¹

Levels of poor mental health, in other words, are not evenly distributed across the

population but fall heaviest upon those more likely to be subject to past and/or present

circumstantial harms. Many of these harms can be further compounded by limited access to

good treatments, poor efficacy of many existing treatments, and the burden of suffering

unrecognised iatrogenic harms.

The two reports published by the United Nations in 2017 also called for two fundamental

reforms to mental health sectors internationally to address the current crisis caused by

over-reliance on biomedical ideas and interventions. These are:

1) Wider implementation of psychological and social support for people with

mental health difficulties (relational, community-based and group/peer support)

2) Greater attention should be paid to tackling the social causes of distress:

inequality, poverty, abuse, discrimination, over-work and social exclusion.

Both UN reports asserted that these vital reforms were being neglected due to three

common obstacles that have held back reform over recent decades.

The first obstacle is dominance of the biomedical model in mental health care - an approach

that frames most mental distress as medical illness, and which favours biomedical

explanations and interventions like psychiatric drugs. The UN reports explain that the

dominance of this approach has led to an overreliance on unnecessary prescribing, the

neglect of effective psychological, community and social alternatives, and the

misrepresentation of the nature and causes of mental distress as primarily medical rather

than social, relational or psychological. It has also largely led professionals to overlook the

complex social and psychological determinants of distress, to the detriment of individual

and public health.

The second obstacle has been the mutually beneficial financial links between psychiatry and

the pharmaceutical industry, including the biased use of evidence to shore up the dominant

biomedical approach. During the psychiatric drug boom of the 1980s, 1990s and 2000s, the

pharmaceutical industry allocated substantial financial resources towards promoting

psychopharmaceuticals in the media and throughout public, professional and political

communities.

This concerted effort involved direct financial targeting of academic and medical

professionals, alongside funding patient advocacy groups, charities and other mental health

organisations. The influence of these financial resources have extended across other facets

of the mental health sector, including policy-making, education, clinical practice and

research activities. Psychiatric professionals have been the primary beneficiaries of research

funding, consultancy fees, speakers’ fees, sponsorship, donations and other contributions

from industry entities.⁴²

Research indicates that such forms of remuneration bias recipients in favour of industry

products, thereby skewing educational, research and clinical practices in pro-industry

directions.

In essence, this systemic entanglement of psychiatry with the pharmaceutical industry has

undermined the objectivity and independence of mental health professionals and

information and has, according to one UN report, corrupted research and the dissemination

of information to the extent that ‘our collective knowledge about mental health had

become tainted’.⁴³ An example of this bias ‘is the use of evidence to inform people with mild

and moderate forms of depression that they should receive psychotropic medications

(antidepressants), despite the clear evidence that they should not. This is even more

shocking when we know that other non-biomedical interventions are more effective, such

as the ones targeting relationships and the social and underlying determinants of mental

health, rather than the brain.’⁴⁴

The excessive use and misuse of psychiatric medications has ultimately created a serious

human rights issue, by denying us the right of access to safer and more effective forms of

mental health care.

The third obstacle identified in the report is power asymmetries in policy making, medical

education, research and care relationships. In short, the dominance of biomedical thinking,

leadership and practice has side-lined the voices and concerns of harmed patients as well as

those advocating for wider systemic reform of our mental health services.

These power asymmetries have been further entrenched by the industry’s financial

sponsorship of drug regulatory agencies, and by the absence of any regulation which would

require all UK medical professionals to publicly report their annual industry payments, as

they must now do in the United States under the Sunshine Act. Currently, the power that

industry is still able to exert though undeclared financial conflicts of interest goes largely

unrecognised and unchallenged due to a lack of financial transparency rules.

### Six principles for mental health reform

In order for the Government to address these obstacles and reform the mental health

sector along the lines consistent with the evidence base, the following six principles must be

adopted:

1. Mental health problems are mostly about our circumstances and

relationships

Research has demonstrated that traumatic interpersonal events such as violence, abuse,

neglect, bullying and discrimination, especially in childhood, are key causal factors in most

mental health difficulties. This includes both specific events and constant low-level

background stressors. The damaging effects can be mitigated by trusting and secure

relationships within families, schools and communities. Relationships, both formal and

informal, are central to healing, and must be the core focus of all service provision. Services

should therefore aim to offer relational support to everyone, with specific trauma-informed

therapies where appropriate. Staff themselves must be appropriately trained and well-

supported in order to carry out this demanding work.

2. Mental health problems arise within our social environments

Economic insecurity and inequality cause emotional distress in their own right, while

increasing the likelihood of traumatic events and relational conflict. They also reduce access

to restorative and supportive resources, compounding an already significant health

inequality. Poverty is a major underlying cause of mental distress (sometimes said to be the

cause of the causes), as it results in debt, poor housing, inadequate nutrition and many

other adversities, which place people under extreme pressure. Poverty erodes family and

community life and blights children’s early lives, making poor mental health almost

inevitable. Ensuring financial, social and material support for families, schools and

communities will significantly reduce distress and hence the need for referrals.

3. Mental health problems are exacerbated by societal messages

We must challenge widespread cultural norms, pressures and messages that lead to

emotional distress in the general population. We know that an over-emphasis on

appearance, lifestyle, competition and consumerism adversely affects wellbeing. Perceived

failure to live up to societal expectations results in feelings of inadequacy, shame and

worthlessness for both children and adults. Rather than framing this as an individual illness

or disorder, we must tackle the unrealistic social expectations that generate distress. We

must also beware of framing difficult yet understandable experiences as mental health

problems that only trained experts can ‘treat’. While well-intended, this message can be

disempowering to all, including parents and teachers, make us afraid of our emotions and

undermine our natural resilience.

4. Positive narratives and language are needed for recovery

Describing people’s problems as individual deficits or disorders is not only contrary to most

of the evidence, but has been shown to increase shame, stigma, pessimism, despair and

disempowerment. This in turn contributes to ever-increasing referrals for interventions that

may not be addressing root causes. Instead, we need to build on existing approaches, which

support people to create positive narratives about surviving difficult circumstances and

finding new ways forward. There are many examples of successful, non-medical community

and peer-led projects which draw on shared experiences, strengths and resources.

5. Psychiatric drugs should be used with caution and over-prescribing must be

reduced

Nearly a quarter of the adult population is prescribed a psychiatric drug each year, with

evidence showing widespread over-prescribing, leading to adverse effects and economic

costs. Such over-prescribing needs to be reversed and provision for non-medical alternatives

significantly increased.

While psychiatric drugs have a limited role for some more serious mental health problems,

they cannot resolve relational or social adversities and when widely prescribed may do

more harm than good. People should be enabled to give fully informed consent, based on

awareness of the whole range of harms and benefits associated with drug treatment.

Offering ‘a pill for every social ill’ does not work and in some cases exacerbates the original

problems. Furthermore, long-term use of psychiatric medication is associated with many

adverse effects, including weight gain, neurological effects, negative sexual effects, severe

withdrawal effects and higher all-cause mortality.

6. Research should focus on better psychosocial provision

Much current and proposed future research is based on the hope that individualised

solutions - both medical and psychological - will help people whose problems are rooted in

relational and social issues. Decades of investigation has shown this approach is failing. We

need to secure funding for the many successful psychosocial projects and encourage all

services to move in these new socially informed directions. We need to identify barriers to

change in our system and how to overcome them.

In applying these principles, we will be moving in the direction recommended by the World

Health Organisation and the United Nations, which now call for us to move away from the

biomedical model and privilege a de-medicalised, psychosocial, person-centred and human

rights-based approach. “Mental health and wellbeing are strongly associated with social,

economic and physical environments, as well as poverty, violence and discrimination.

However, most mental health systems focus on diagnosis, medication and symptom

reduction, neglecting the social determinants that affect people’s mental health.”⁴⁵ As the

UN Special Rapporteur continued: “The urgent need (is) to…..target social determinants and

abandon the predominant medical model that seeks to cure individuals by targeting

‘disorders’”.⁴⁶If we can do all this, we will be improving not just people’s emotional

wellbeing but every aspect of their lives, while contributing to the betterment of mental and

emotional health across society.

### Calls for action

Adopting the principles described above to achieve the desired shift in balance will require

many reforms. Facilitating this shift is not the sole responsibility of the government; it

requires everyone involved in the UK mental health system to actively play a part.

The Beyond Pills APPG will advocate for nine calls to action under the headings of Services,

Regulation, Education and Public & Professional Awareness in order to help achieve the

desired change. This is not an exhaustive list but rather areas of focus that are within the

scope of the mission of the APPG.

### Services

1. Boost provision for social interventions, including social prescribing and

community-based resources

As the WHO states, “mental health and well-being are strongly associated with social,

economic and physical environments, as well as poverty, violence, and discrimination.

However, most mental health systems focus on diagnosis, medication and symptom

reduction, neglecting the social determinants that affect people’s mental health.”⁴⁷ We call

upon the Government to upscale social and community interventions, in particular social

prescribing services for people with mild to moderate mental health issues.

Evidence shows that social prescribing can have a positive impact on a very wide range of

outcomes, including decreases in loneliness, improvements in mental health, in increased

social connections and in overall wellbeing.⁴⁸ Social prescribing seeks to reduce health

inequalities. Vast differences in the social impacts on health, individual health behaviours,

illness, disability, availability of services and activities, quality and experience of care,

proximity to accessible natural spaces, geography and wealth mean that health outcomes

are not the same for everyone, with marginalised and vulnerable people often experiencing

the worst outcomes. Social prescribing may address both the circumstances that make an

individual unhealthy and their symptoms by supporting individuals to address their unmet

social needs.

Social prescribing can lead to reduced health service usage within both primary and

secondary care. For example, an evaluation of the social prescribing service in Shropshire

showed a 40% reduction in GP appointments for people who had accessed social prescribing

after three months. Evaluations consistently show a favourable social return on investment,

with a large study by the University of Sheffield showing a social return of £3.42 for every £1

invested.⁴⁹

By reducing the number of GP appointments and prescriptions, social prescribing can also

help the NHS to reduce its carbon footprint. It can also promote connection with nature,

which has been shown to encourage pro-environmental behaviours.

2. Fund and deliver community-based mental health hubs for people of all

ages

Labour has announced that it will tackle the crisis in children’s and young people’s mental

health by measures including an open access mental health hub for every community for up

to 25s. It is essential that such hubs do not simply increase the number of children

diagnosed and prescribed medication through a ‘more-of-the-same’ biomedical approach.

We therefore call upon the Government to offer de-medicalised mental health hubs for

children - and adults - based on an approach that integrates social prescribing (to help with

the social determinants of mental health concerns), lifestyle support and psychosocial

interventions.

These local mental health and wellbeing hubs would adapt to the needs of the local

community through direct involvement, aiming to support people through emotional

difficulties and prevent them escalating, as well as providing targeted resources for those

who need it.

There are examples where this kind of service is already offering vulnerable people support

of different kinds. In North Cornwall, for instance, communities are setting up their own

walk-in hubs, supported by local NHS primary care teams and by volunteers. Across

Cornwall, pain cafes run by social enterprises in tandem with NHS personalised care help

patients suffering chronic pain to learn self-management techniques.⁵⁰

3. Fund and deliver a national 24-hour prescribed drug withdrawal helpline

and website

The World Health Organisation states: “Support should be provided to help people safely

withdraw from treatment with drugs.”⁵¹

Thousands of patients are currently suffering debilitating and sometimes life-changing

withdrawal effects from psychiatric medicines which they have taken as prescribed, and for

which there is currently almost no NHS support. They are experiencing harm as a direct

result of NHS treatment, and there is therefore a moral imperative for the health service to

provide support for this cohort.

Public Health England’s 2019 Prescribed Medicines Review⁵² stated that 1 in 4 of the adult

population in England had been prescribed drugs associated with dependence and

withdrawal in 2017-18. It also identified there is currently very limited support available to

patients seeking to withdraw from such drugs.

Recent research also reveals that 5.4 million people in England are being unnecessarily

prescribed dependence forming psychiatric and painkilling drugs, costing the NHS more than

£560M per year.⁵³

In addition to the reduction of the harms of unnecessary dependence, there are substantial

savings to be made that justify investment in dedicated services to help patients come off

these drugs safely. Unlike illicit drugs, there is currently almost no funded provision of these

services.

One of the key recommendations of the PHE review is the creation of a UK-wide 24-hour

helpline and associated website to provide expert advice and support (including tapering

and drug information) for patients, their families and doctors, linked to local in-person

withdrawal support services.

The Government must fund and deliver this helpline as soon as possible to support the

many thousands of patients who have been harmed by the drugs they were prescribed, and

who currently have little or no withdrawal support at all.

4. Reverse the rate of unnecessary antidepressant prescribing

In December 2023, Beyond Pills APPG members and experts as well as politicians and

patient representatives called for the Government to reverse the rate of antidepressant

prescribing. As we collectively wrote in the British Medical Journal, over the past decade

antidepressant prescriptions have almost doubled in England, rising from 47.3 million in

2011 to 85.6 million in 2022-23. Over 8.6 million adults in England are now prescribed them

annually (nearly 20% of adults),⁵⁴ with prescriptions set to rise over the next decade. In

addition, the average duration of time for which a person takes an antidepressant has

doubled between the mid-2000s and 2017, with around half of patients now classed as long-

term users.⁵⁵

While rising long term use is associated with many adverse effects, including withdrawal

effects,⁵⁶ it is not associated with an improvement in mental health outcomes at the

population level, which, according to some measures, have worsened as antidepressant

prescribing has risen.⁵⁷ Questions remain about the extent to which poor outcomes are

fuelled by such adverse effects together with the poor efficacy of antidepressants for many

groups. Multiple meta-analyses have shown antidepressants to have no clinically meaningful

benefit beyond placebo for all patients except those with the most severe depression,⁵⁸

which is why guidance from the National Institute for Health and Care Excellence states that

they should not be routinely prescribed as first line treatment for less severe depression,

while still respecting the importance of shared decision-making.

Despite this, rates of prescribing to patients with mild and moderate depression remain

unacceptably high.⁵⁹ Furthermore, there are now evidence-based objections to prescribing

antidepressants for people with chronic pain, where efficacy is very low,⁶⁰ alongside

evidence of disproportionate prescribing to women, older people and those living in

deprived areas.⁶¹ This raises questions about the extent to which we are wrongly

medicalising and medicating the effects of disadvantage and deprivation.

As well as the human costs of unnecessary antidepressant prescribing, there is evidence of

substantial unnecessary economic costs being incurred by the NHS in England of up to £58m

annually⁶² - money that could be better spent boosting non-pharmacological provision.

A reversal in the rate of antidepressant prescribing can be achieved by following through

with various public health recommendations, in line with the NHS National Medicines

Optimisation Opportunities 2023-24,⁶³ which include:

- Stopping the prescribing of antidepressants for mild conditions for new patients
- Adhering to the 2022 NICE guidance on safe prescribing and withdrawal
management, including properly informed consent and regular review of harms

and benefits

- Including the reduction of antidepressant prescribing as an indicator in the NHS
Quality and Outcomes Framework

- Funding and delivering local withdrawal services integrated with social
prescribing, lifestyle medicine and psychosocial interventions, in line with the

NHS framework for action ‘Optimising personalised care for adults prescribed

medicines associated with dependence or withdrawal symptoms’

- Funding and delivering a national 24-hour prescribed drug withdrawal helpline
and website (see above).

### Regulation

5. Reform the MHRA, the regulator of medicines in the UK

In 2005, the Health Select Committee issued a report highlighting concerns regarding the

Medicines and Healthcare Products Regulatory Agency (MHRA); this emphasised its

proximity to the pharmaceutical industry, compromising its ability to safeguard public

health.⁶⁴ The report noted many instances of regulatory capture where industry funding of

the MHRA and former industry professionals in leadership roles at the MHRA have both

significantly undermined its impartiality and regulatory standards, leading to systemic

favouring of industry interests over patient safety.

Despite recommendations for systemic reforms to ensure regulatory effectiveness in the

public interest, subsequent investigations, including a recent BMJ inquiry in 2022, reveal

persistent issues of conflicts of interest and overly lenient regulation at the MHRA.⁶⁵ The All-

Party Parliamentary Group (APPG) on Pandemic Response and Recovery has echoed these

problems, citing "serious patient safety concerns" about the MHRA, "owing to the state of

regulatory capture”.⁶⁶ Experts have emphasised the need for rigorous, independent

regulation to restore public trust and ensure patient safety in the approval and monitoring

of medicines.

6. Implement a UK Sunshine Act to improve transparency of financial conflicts

of interest

In addition to the problems emerging from conflicts of interests and regulatory capture at

the MHRA, there remains a lack of transparency regarding financial conflicts of interest in

medicine overall.⁶⁷ Extensive research highlights the influence of industry financial ties on

psychiatric practices, favouring pharmaceuticals. Poor transparency has permitted conflicts

of interest to thrive, unrestrained by any threat of reputational reprisals.⁶⁸ Despite clear

evidence of bias, there is no legislation obliging doctors in the UK to report potential

financial conflicts. In contrast, the Sunshine Act in the US has, since 2010, legally mandated

that doctors publicly disclose industry payments on an annual basis.

We urge the Government to enact a similar Sunshine Act to enhance transparency, while

simultaneously addressing regulatory capture at the Medicines and Healthcare products

Regulatory Agency (MHRA). Structural reforms, including establishing independent

evaluation bodies like Germany's Institute for Quality and Efficiency in Health Care and

making the MHRA free of industry funding, are necessary to ensure unbiased decision-

making and safeguard patient safety. Additionally, a drug and vaccine safety board

independent of the regulator is proposed to investigate incidents of patient harm.

### Education and training

7. Integrate Social Emotional Learning (SEL) into the national curriculum

Ever-increasing numbers of children are diagnosed with anxiety, depression and other

mental health conditions. In 2023, 20% of children and young people aged 5 to 16 were

identified as having probable mental health conditions, a considerable increase from one in

nine in 2017.⁶⁹ This surge in poor mental health has adverse impacts on educational

engagement, personal relationships, and long-term prospects.

Secondary schools particularly struggle to adequately support students with mental health

issues, exacerbating the problem (e.g. a survey of 1271 secondary school children,

conducted by Mind in 2021, found that 78% of the children reported that school made their

mental health worse).⁷⁰ The implications extend beyond the educational sphere, affecting

employment opportunities, health outcomes and societal wellbeing.

To help tackle this, Social and Emotional Learning (SEL) should become an essential

component of education within our society and be incorporated into the national

curriculum. SEL is an educational approach that focuses on developing social and emotional

skills in young people. It enables them to acquire the knowledge, skills and attitudes

necessary for effectively managing emotions, achieving personal and collective goals,

fostering empathy, nurturing supportive relationships and the capacity to make responsible

and compassionate decisions.

SEL strategies should be incorporated within the broader framework of a Whole Systems

Approach in schools. The Whole Systems Approach emphasises collaboration among

teachers, administrators, students, parents and the community to create a cohesive

environment supportive of good mental health.⁷¹ This approach goes beyond traditional

academic instruction to address the social, emotional and behavioural needs of students, by

way of personalised learning initiatives, multi-tiered support systems and partnerships with

community organisations that can help address social and economic adversity. By focusing

on the interconnectedness of all elements within the school ecosystem, the Whole Systems

Approach aims to improve student outcomes, mental health and overall school

performance.

The five core competencies of SEL (self-awareness, self-management, social awareness,

relationship skills and responsible decision-making) form the foundation of SEL

programmes. These competencies are developed through various school learning

experiences and interactions, promoting holistic development among students.

Extensive research demonstrates the positive impact of SEL on student well-being, academic

72 73 74 achievement, and future life outcomes. SEL interventions have been associated with

reduced emotional distress, improved academic performance⁷⁵ and enhanced social and

emotional skills among participants.⁷⁶ Moreover, SEL initiatives yield substantial benefits

that outweigh their costs, offering a high return on investment in terms of societal

outcomes.⁷⁷

We urge the Government to integrate SEL into the national curriculum and within the

existing Whole Systems Approach operating in many schools, as it offers a promising

response to the growing mental health challenges facing children and young people.

8. Improve the education and training of health professionals

Reforming the UK’s mental health care system requires a critical reappraisal of the training

and education of health professionals. This training, which is crucial at both undergraduate

and postgraduate levels, must align with the emerging socio-psycho-bio, whole person

approach to health and care.

At the undergraduate level, university curricula for health professionals should integrate

comprehensive modules and assessments focusing on:

- appropriate and necessary prescribing versus overprescribing
- safe deprescribing
- holistic mental health approaches such as social prescribing, lifestyle medicine and
psychosocial interventions

- emphasising the understanding of mental health within social, economic, and
environmental contexts.

Similarly, for postgraduate training, continued professional development (CPD) programmes

should concentrate on safe prescribing and deprescribing, social prescribing, and

community engagement. To implement these educational reforms, collaboration between

government, the NHS, educational institutions and professional bodies is essential.

Dedicated funding should be allocated by the Government for the development and

updating of curricula, and robust mechanisms set up to evaluate the effectiveness of new

training modules. Government support is crucial to mandate the inclusion of socio-psycho-

bio approaches in medical and healthcare training.

The Beyond Pills APPG is currently establishing a special interest group for trainees and

medical students with the aim of developing educational materials that can be used for both

undergraduates and postgraduates.

Through partnership and collaboration with key educational bodies, the APPG intends to

embed key principles of safe deprescribing and non-medical interventions at the core of the

essential curricula for current and emerging health professionals.

Our aim is to ensure that today's and tomorrow's healthcare professionals are equipped to

deliver comprehensive, personalised care for those affected by mental health problems of

all kinds.

We call for the reform of the training of health professionals, aligning undergraduate and

postgraduate education with a socio-psycho-bio approach. This entails integrating modules

on appropriate prescribing, safe deprescribing, holistic mental health approaches and

understanding mental health in its broader social/cultural contexts. To implement and fund

such reforms requires a concerted collaboration between government, the NHS, educational

institutions and professional bodies.

### Public and professional awareness

9. De-medicalise mental health language in both public and professional

spaces

In 2015 the British Psychological Society (BPS) published Guidelines on Language in Relation

to Functional Psychiatric Diagnosis.⁷⁸ These guidelines presented a different set of mental

health terms that avoid labelling, pathologising and depoliticising emotional distress. They

offer more neutral terminology in order to prevent the negative effects associated with

using medicalised language, while promoting relational and contextual understandings and

responses to distress.

The movement towards using more formulation-based and non-medical mental health

meanings and terms is rooted in evidence demonstrating the often adverse emotional and

psychological effects of embracing medical terminology. While some individuals may feel

validated by interpreting their distress in medical or pathologising terms, and while framing

distress medically is currently a prerequisite, in most cases, for receiving support, research

nevertheless shows that framing distress as mental ‘disorder’, ‘illness’ or ‘dysfunction’ can

also hinder recovery and increase stigma, especially if individuals erroneously believe their

problems to stem from biological abnormalities.⁷⁹ Being medicalised should therefore not

be a precondition for receiving mental health care and support.

For example, people who come to believe their problems are due to chemical imbalances

experience worse pessimism about their recovery, increased self-stigma, more negative

expectations and self-blame⁸⁰ as well as more depressive symptoms after the close of their

treatment⁸¹, compared to people who reject this hypothesis. Similar results have also been

found for those who embrace biogenetic explanations for their distress,⁸² which regularly

increase stigmatising attitudes among patients and mental health professionals⁸³ as well as

hopelessness in those believing their conditions to be chronic.⁸⁴

Furthermore, medicalising distress (even when severe) may make it challenging for

individuals to eventually perceive themselves as healthy participants in normal life or in

control of their fate. It can foster dependency on psychiatric authority and prompt

individuals to downgrade their prospects and ambitions for the future. Framing emotional

problems in terms of an illness or disorder is also more likely to kindle fear, suspicion and

hostility in others than if we articulate those very same problems in non-medical,

psychological terms.⁸⁵⁸⁶

Even seemingly benign labels like depression can lead to negative perceptions, with those

diagnosed being more likely to be viewed as having frail wills or character flaws, as being

afflicted by personal weakness, or as being lazy and unpredictable.⁸⁷ More serious diagnoses

like schizophrenia can exacerbate stigma and perceptions of being dangerous, which can

compound a person’s sense of isolation through social rejection.⁸⁸ As the largest meta-study

into how medicalisation impacts outcomes concluded: ‘Medicalisation is no cure for stigma

and may create barriers to recovery.’⁸⁹

We call upon the Government to cease making being medicalised a precondition for

receiving any care and support. Removing this precondition will enable us to move away

from describing real everyday struggles in terms of illness and disorder, towards accepting

that such problems often have clear roots in social, relational and psychological adversities

that need to be acknowledged and addressed. We need to move towards narrative-based

formulations that use more neutral terms in how we discuss and manage emotional distress

in both public and professional contexts. This shift, while still recognising that such problems

are real and require support and care, will also help reduce the stigma associated with

mental health challenges and likely improve outcomes.

### Conclusion

It is evident that the current state of mental health care in the United Kingdom requires

urgent and comprehensive reform. The challenges outlined in this report underscore the

need for a paradigm shift away from the traditional biomedical model that fuels the over-

medicalisation and medicating of distress, towards a more holistic, person-centred approach

that more fully recognises and addresses the social, economic and psychological

determinants of mental health.

Over the past four decades, significant investments have been made in mental health

services and research yet outcomes have not improved and, according to some measures,

they have worsened. Rates of poor mental health have continued to grow while the

mortality gap between those with severe mental health issues and the general population

has widened. Despite nearly a quarter of the adult UK population being prescribed

psychiatric drugs each year, their efficacy in improving functional outcomes remains

questionable and concerns about overprescribing, serious long-term harms and

adverse/withdrawal effects persist.

The UN and the WHO have now issued calls for fundamental reforms in mental health care,

emphasising the importance of psychological and social support alongside efforts to address

the underlying social determinants of mental distress. These calls have been echoed by

numerous experts and organisations, highlighting the need to move away from the

dominance of the biomedical model and prioritise interventions that address the root

causes of mental health issues.

Six key principles for mental health reform have been proposed, emphasising the

importance of understanding mental health problems within the context of individuals'

circumstances and relationships, as well as their broader social and economic environments.

These principles advocate for a reduction in the overprescribing of psychiatric drugs,

increased funding for psychosocial interventions, and a shift towards a de-medicalised

understanding of mental health issues.

The Beyond Pills APPG has identified nine specific recommendations for policy changes

relevant to its mission that would contribute to the needed shift, including reversing

unnecessary antidepressant prescribing, establishing a national withdrawal support

helpline, investing in community-based mental health hubs and social prescribing,

implementing regulatory reform and a UK Sunshine Act, integrating social and emotional

learning programmes within the national curriculum, demedicalising mental health

language, as well as improving the education and training of health professionals. These

recommendations broadly align with the World Health Organisation's guidelines for

promoting mental health and well-being, emphasising the importance of social

interventions and community support networks.

By adopting these principles and supporting these reforms, the Government can help

improve individual mental health outcomes, address broader social inequalities and

promote overall societal wellbeing. By prioritising holistic, person-centred approaches to

mental health care and addressing the social determinants of mental distress, we can build a

healthier society for all.

Authors:

Dr James Davies (lead author)

Dr Anne Guy

Luke Montagu

Sarah Stacey

Dr Bogdan Chiva Giurca

Dr Lucy Johnstone

NHS Business Authority 2023) NHS releases mental health medicines statistics for 2022/2023 in England. Website: https://media.nhsbsa.nhs.uk/news/nhs-releases-mental-health-medicines-statistics-for-20222023-in-england

2 NHS England (2023) Mental Health of Children and Young People Surveys. Website: https://www.england.nhs.uk/2023/11/one-in-five-children-and-young-people-had-a-probable-mental-disorder-in-2023/

3 Children’s Commissioner (2024) Over a quarter of a million children still waiting for mental health support. Website: https://www.childrenscommissioner.gov.uk/blog/over-a-quarter-of-a-million-children-still-waiting-for-mental-health-support/

4 MIND (2013) We Still Need to Talk: a report on access to talking therapies. Website: https://www.mind.org.uk/media-a/4248/we-still-need-to-talk_report.pdf

5 NHS Mental Health Taskforce Strategy. The Five Year Forward View for Mental Health. (website), 2020 https://www.england.nhs.uk/wp-content/uploads/2016/02/Mental-Health-Taskforce-FYFV-final.pdf (accessed Sep 2020)

6 Davies, J (2022) Sedated: how capitalism caused our mental health crisis. London: Atlantic Books

Middleton H, Moncrieff J. “They won’t do any harm and might do some good”: time to think again on the use of antidepressants?Br J Gen Pract2011;61:47-9. doi:10.3399/bjgp11X548983 pmid:21401992

7 Kristen L. Syme, Edward H. Hagen. Mental health is biological health: Why tackling “diseases of the mind” is an imperative for biological anthropology in the 21st century, April 2019. https://doi.org/10.1002/ajpa.23965

8 House of Commons (2023) UK Disability Statistics: prevalence and life experiences. Website: https://researchbriefings.files.parliament.uk/documents/CBP-9602/CBP-9602.pdf

9 Paul, S.M., Potter, W.Z. Finding new and better treatments for psychiatric disorders. Neuropsychopharmacol. 49, 3–9 (2024). https://doi.org/10.1038/s41386-023-01690-5

10 D. Lawrence et al. (2013) The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers BMJ; 346 doi: https://doi.org/10.1136/bmj.f2539

11 Liselotte D. de Mooij Front. (2019) Dying Too Soon: Excess Mortality in Severe Mental Illness Front. Psychiatry, .https://doi.org/10.3389/fpsyt.2019.00855

And: NHS Digital (2020) Mental Health Bulletin: Annual report from MHMDS returns - England, 2011-12, further analysis and organisation-level data, website:

https://digital.nhs.uk/data-and-information/publications/statistical/mental-health-bulletin/mental-health-bulletin-annual-report-from-mhmds-returns-england-2011-12-further-analysis-and-organisation-level-data (accessed Sep 2020)

12 Center for Mental Health (2024) The economic and social costs of mental ill health. Webpage https://www.centreformentalhealth.org.uk/wp-content/uploads/2024/03/CentreforMH_TheEconomicSocialCostsofMentalIllHealth.pdf

13 Pūras, D. Statement by Mr Dainius Pūras, Special Rapporteur on the right of everyone to the enjoyment of the highest attainable standard of physical and mental health at the 35th session of the Human Rights Council, 2017, [website] https://www.ohchr.org/en/NewsEvents/Pages/DisplayNews.aspx?NewsID=22052&LangID=E (accessed Feb 2020). And: Pūras D. Right of everyone to the enjoyment of the highest attainable standard of physical and mental health. Human Rights Council. United Nations. 2019, [website] https://www.un.org/en/ga/search/view_doc.asp?symbol=A/HRC/41/34 (accessed Feb 2020).

14 Research summarised in: Johnstone, L. & Boyle, M. with Cromby, J., Dillon, J., Harper, D., Kinderman, P., Longden, E., Pilgrim, D. & Read, J. (2018). The Power Threat Meaning Framework: Towards the identification of patterns in emotional distress, unusual experiences and troubled or troubling behaviour, as an alternative to functional psychiatric diagnosis. Leicester: British Psychological Society.

15 A counter argument is that there is no biomedical model, but rather a biopsychosocial model. While that may be true in theory, in practice the interventions and symbolism preferred throughout our health systems are largely biomedical.

World Health Organization (2022). World mental health report: transforming mental health for all. Geneva: World Health Organization.

17 Pickett KE, Wilkinson RG. (2010) Inequality: an underacknowledged source of mental illness and distress. Br J Psychiatry;197:426‐8.

18 Kivimäki M, Batty GD, Pentti J et al. Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi‐cohort study. Lancet Public Health 2020;5:e140‐9.

19 Kim TJ, von dem Knesebeck O. Perceived job insecurity, unemployment and depressive symptoms: a systematic review and meta‐analysis of prospective observational studies. Int Arch Occup Environ Health 2016;89:561‐73.

20 Kivimäki M, Batty GD, Pentti J et al. Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi‐cohort study. Lancet Public Health 2020;5:e140‐9.

21 Lund C, Breen A, Flisher AJ et al. Poverty and common mental disorders in low and middle income countries: a systematic review. Soc Sci Med 2010;71:517‐28.

22 Pourmotabbed A, Moradi S, Babaei A et al. Food insecurity and mental health: a systematic review and meta‐analysis. Public Health Nutr 2020;23:1778‐90

23 Singh A, Daniel L, Baker E et al. Housing disadvantage and poor mental health: a systematic review. Am J Prev Med 2019;57:262‐72.

24 Guan N, Guariglia A, Moore P et al. Financial stress and depression in adults: a systematic review. PLoS One 2022;17:e0264041.

25 Pascoe EA, Richman LS. Perceived discrimination and health: a meta‐analytic review. Psychol Bull 2009;135:531‐54.

26 McLaughlin KA. Future directions in childhood adversity and youth psychopathology. J Clin Child Adolesc Psychol 2016;45:361‐82.

27 Castelpietra G, Knudsen AKS, Agardh EE et al. The burden of mental disorders, substance use disorders and self‐harm among young people in Europe, 1990‐2019: findings from the Global Burden of Disease Study 2019. Lancet Reg Health Eur 2022;16:100341

28 Office of National Statistics (2021) Children whose families struggle to get on are more likely to have mental disorders. Website: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/childhealth/articles/childrenwhosefamilies struggletogetonaremorelikelytohavementaldisorders/2019-03-26

29 Kirkbride JB, Anglin DM, Colman I, Dykxhoorn J, Jones PB, Patalay P, Pitman A, Soneson E, Steare T, Wright T, Griffiths SL. The social determinants of mental health and disorder: evidence, prevention and recommendations. World Psychiatry. 2024 Feb;23(1):58-90. doi: 10.1002/wps.21160. PMID: 38214615; PMCID: PMC10786006.

30 Ng, L.C., Hook, K., Hailemariam, M. et al. Experience of traumatic events in people with severe mental illness in a low-income country: a qualitative study. Int J Ment Health Syst 17, 45 (2023). https://doi.org/10.1186/s13033-023-00616-4

31 Felitti VJ, Anda RF, Nordenberg D et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: the Adverse Childhood Experiences (ACE) study. Am J Prev Med 1998;14:245‐58.

32 Felitti VJ, Anda RF, Nordenberg D et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: the Adverse Childhood Experiences (ACE) study. Am J Prev Med 1998;14:245‐58

33 Mann F, Wang J, Pearce E et al. Loneliness and the onset of new mental health problems in the general population. Soc Psychiatry Psychiatr Epidemiol 2022, 57:2161‐78.

34 Lacey RE, Minnis H. Practitioner review: Twenty years of research with adverse childhood experience scores – Advantages, disadvantages and applications to practice. J Child Psychol Psychiatry 2020;61:116‐30.

35 Burn‐Murdoch J. Smartphones and social media are destroying children's mental health. Financial Times, March 10,

Research summarised in: Johnstone, L. & Boyle, M. with Cromby, J., Dillon, J., Harper, D., Kinderman, P., Longden, E., Pilgrim, D. & Read, J. (2018). The Power Threat Meaning Framework: Towards the identification of patterns in emotional distress, unusual experiences and troubled or troubling behaviour, as an alternative to functional psychiatric diagnosis. Leicester: British Psychological Society.

37 Whitaker, Robert (Spring 2005). "Anatomy of an Epidemic: Psychiatric Drugs and the Astonishing Rise of Mental Illness in America" (PDF). Ethical Human Psychology and Psychiatry. 7 (I). Springer: 1. Retrieved October 11, 2010.

38 Fava GA, Rafanelli C. Iatrogenic Factors in Psychopathology. Psychother Psychosom. 2019;88(3):129-140. doi: 10.1159/000500151. Epub 2019 May 14. PMID: 31085917

39 Davies, J (2022) Sedated: how modern capitalism created our mental health crisis. London: Atlantic Books.

40 Hiam, L., et al. (2024). NHS and the whole of society must act on social determinants of health for a healthier future. BMJ. doi.org/10.1136/bmj-2024-079389.

41 Kirkbride JB, Anglin DM, Colman I, Dykxhoorn J, Jones PB, Patalay P, Pitman A, Soneson E, Steare T, Wright T, Griffiths SL. The social determinants of mental health and disorder: evidence, prevention and recommendations. World Psychiatry. 2024 Feb;23(1):58-90. doi: 10.1002/wps.21160.

42 Goldacre, B. (2012) Bad Pharma: how drug companies mislead doctors and harm patients. Ben Goldacre . London: Fourth Estate.

43 Ibid.

44 Davies, J (2022) Sedated, why capitalism is causing our mental health crisis London: Atlantic Books & Middleton H, Moncrieff J. “They won’t do any harm and might do some good”: time to think again on the use of antidepressants?Br J Gen Pract2011;61:47-9.

45 Mental health, human rights and legislation: guidance and practice. Geneva: World Health Organization and the United Nations (represented by the Office of the United Nations High Commissioner for Human Rights); 2023. Licence: CC BY-NC- SA 3.0 IGO.p. xvii

46 Pûras, D. Report of the Special Rapporteur on the Right of Everyone to the Enjoyment of the Highest Attainable Standard of Physical and Mental Health UN, 2017

47 Mental health, human rights and legislation: guidance and practice. Geneva: World Health Organization and the United Nations (represented by the Office of the United Nations High Commissioner for Human Rights); 2023. Licence: CC BY-NC- SA 3.0 IGO.

48 National Academy for Social Prescribing Read the Evidence. Website: https://socialprescribingacademy.org.uk/read-the-evidence/

49 Polley, M., Seers, H., Toye, O., Henkin, T., Waterson, H., Bertotti, M. and Chatterjee, H.J. (2023). Building the economic evidence case for social prescribing.. London: National Academy for Social Prescribing.https://socialprescribingacademy.org.uk/media/wemjbqtw/building-the-economic-case-for-social-prescribing-report.pdf

50 BBC News (2013) New NHS pain cafes launch in Cornwall, website: https://www.bbc.co.uk/news/uk-england-cornwall- 64451040

51 World Health Organization (2023). Mental health, human rights and legislation: guidance and practice. In Mental health, human rights and legislation: guidance and practice, p.74

52 Public Health England Prescribed Medicines Review (2019) Website: :

https://www.gov.uk/government/publications/prescribed-medicines-review-report

53 Davies J, Cooper RE, Moncrieff J, Montagu L, Rae T, Parhi M. The costs incurred by the NHS in England due to the unnecessary prescribing of dependency-forming medications. Addict Behav2022;125:107143. doi:10.1016/j.addbeh.2021.107143 pmid:34674906

NHS Business Services Authority (2023) Medicines used in mental health—England—2015-16 to 2022-23. 6 Jul. Website: https://www.nhsbsa.nhs.uk/statistical-collections/medicines-used-mental-health-england/medicines-used-mental-health-england-201516-202223

55 NHS Digital. Prescriptions dispensed in the community—statistics for England, 2006-2016. 2017. https://digital.nhs.uk/data-and-information/publications/statistical/prescriptions-dispensed-in-the-community/prescriptions-dispensed-in-the-community-statistics-for-england-2006-2016-pas

56 Davies J, Read J, A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based?Addict Behav2019;97:111-21. doi:10.1016/j.addbeh.2018.08.027 pmid:30292574

57 Middleton H, Moncrieff J. “They won’t do any harm and might do some good”: time to think again on the use of antidepressants?Br J Gen Pract2011;61:47-9. doi:10.3399/bjgp11X548983 pmid:21401992

58 Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, Johnson BT. Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS Med2008;5:e45. doi:10.1371/journal.pmed.0050045 pmid:18303940

59 Coupland C, Dhiman P, Morriss R, Arthur A, Barton G, Hippisley-Cox J. Antidepressant use and risk of adverse outcomes in older people: population-based cohort study. BMJ2011;343:d4551. doi:10.1136/bmj.d4551 pmid:21810886 Shim RS, Baltrus P, Ye J, Rust G. Prevalence, treatment, and control of depressive symptoms in the United States: results from the National Health and Nutrition Examination Survey (NHANES), 2005-2008. J Am Board Fam Med2011;24:33-8. doi:10.3122/jabfm.2011.01.100121 pmid:21209342. And Cruickshank G, Macgillivray S, Bruce D, Mather A, Matthews K, Williams B. Cross-sectional survey of patients in receipt of long-term repeat prescriptions for antidepressant drugs in primary care. Ment Health Fam Med2008;5:105-9.pmid:22477855

60 Birkinshaw H, Friedrich CM, Cole P, et al. Antidepressants for pain management in adults with chronic pain: a network meta-analysis. Cochrane Database Syst Rev2023;5:CD014682.pmid:37160297

61 Public Health England Prescribed Medicines Review 2019

62 Davies J, Cooper RE, Moncrieff J, Montagu L, Rae T, Parhi M. The costs incurred by the NHS in England due to the unnecessary prescribing of dependency-forming medications. Addict Behav2022;125:107143. doi:10.1016/j.addbeh.2021.107143 pmid:34674906

63 NHS Business Services Authority. National medicines optimisation opportunities 2022/23. NHS England. 2023.

64 House of Commons Health Committee. The influence of the pharmaceutical industry. Website: http://www.parliament.the-stationery-office.co.uk/pa/cm200405/cmselect/cmhealth/42/42 pdf (accessed 28 March Apr 2024).

65 Demasi M. From FDA to MHRA: are drug regulators for hire? BMJ 2022; 377 :o1538 doi:10.1136/bmj.o1538

66 APPG for Pandemic Response and Recovery. Raising concerns about the MHRA. Website: https://appgpandemic.org/news/mhra-letter-health-select-committee

67 Macleod, S (2021) A sunshine payment act for the UK. BMJ 2021; 374 doi: https://doi.org/10.1136/bmj.n1900 (Published 30 July 2021).

68 Chimonas S, Stahl F, Rothman DJ. Exposing conflict of interest in psychiatry: does transparency matter? Int J Law Psychiatry. 2012 Sep-Dec;35(5-6):490-5. doi: 10.1016/j.ijlp.2012.09.009. Epub 2012 Oct 2.

69 The Mental Health of Children and Young People Survey - NHS (2023) Website: https://digital.nhs.uk/data-and-information/publications/statistical/mental-health-of-children-and-young-people-in-england

70 Mind (2023) Facts and Figures about Young People and Mental Health. Website: https://www.mind.org.uk/about-us/our-strategy/doing-more-for-young-people/facts-and-figures-about-young-people-and-mental-health/

71 Cefai, C., Simões, C. and Caravita, S. (2021) ‘A systemic, whole-school approach to mental health and wellbeing in schools in the EU’ NESET report, Luxembourg: Publications Office of the European Union. doi: 10.2766/50546.

Early Intervention Foundation (2021) Adolescent mental health: A systematic review on the effectiveness of school-based interventions. Website: https://www.eif.org.uk/report/adolescent-mental-health-a-systematic-review-on-the-effectiveness-of-school-based-interventions

73 Education Policy Institute. (2021) Social and emotional learning: An evidence review and synthesis of key issues, Website: https://epi.org.uk/publications-and-research/social-and-emotional-learning/

74 Cipriano C, Strambler MJ, Naples LH, Ha C, Kirk M, Wood M, Sehgal K, Zieher AK, Eveleigh A, McCarthy M, Funaro M, Ponnock A, Chow JC, Durlak J. The state of evidence for social and emotional learning: A contemporary meta-analysis of universal school-based SEL interventions. Child Dev. 2023 Sep-Oct;94(5):1181-1204.

75 Duriak J.A. et al. (2011) The Impact of Enhancing Students’ Social and Emotional Learning: A Meta-Analysis of School- Based Universal Interventions. Child Development 82(1):405-32 DOI:10.1111/j.1467-8624.2010.01564.x

76 Damon E.J. (2015) Early Social-Emotional Functioning and Public Health: The Relationship Between Kindergarten Social Competence and Future Wellness. American Journal of Public Health (AJPH). Published Online November 2015 Website: https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2015.302630

77 CBCE (2015) The Economic Value of SEL, Website: https://www.cbcse.org/publications/the-economic-value-of-social-and-emotional-learning

78 British Psychological Society (2015) Guidelines on Language in Relation to Functional Psychiatric Diagnosis.

79 Angermeyer, M., Matschinger, H. (2005), ‘Causal beliefs and attitudes to people with schizophrenia: trend analysis based on data from two population surveys in Germany’, British Journal of

Psychiatry 186:331–4.

80 Kempa, Joshua J., et al. (2020), ‘Effects of a chemical imbalance causal explanation on

individuals’ perceptions of their depressive symptoms’, Behaviour Research and Therapy 56:47–52

81 Schroder, Hans S. (2020), ‘Stressors and chemical imbalances: Beliefs about the causes of depression in an acute psychiatric treatment sample’, Journal

of Affective Disorders 276:537–45.

82 Kvaalea, Erlend P.,et al. (2013), ‘The “side effects” of medicalization: A meta-analytic review of

how biogenetic explanations affect stigma’, Clinical Psychology Review 33 (6):782–94.

83 Larkings, J. S., and Brown, P. M. (2018), ‘Do biogenetic causal beliefs reduce mental illness stigma in people with mental illness and in mental health professionals? A systematic review’, International Journal of Mental Health Nursing 27:928–41.

84 Berardelli, I., et al. (2019), ‘The Role of Demoralization and Hopelessness in Suicide Risk in Schizophrenia: A Review of the Literature’, Medicina (Kaunas, Lithuania) 55(5):200, https://doi.org/10.3390/medicina55050200.

85 Timimi, S. (2011), ‘Campaign to Abolish Psychiatric Diagnostic Systems such as ICD and DSM’, Website; http://www.criticalpsychiatry.co.uk/index.php?option=com_content&view=article&id=233:campaign-to-abolish-psychiatric-diagnostic-systems-such-as-icd-and-dsm-timimi-s&catid=34:members-publications&Itemid=56.

86 E. Watters (2010), ‘The Americanization of Mental Illness’, New York Times, Website: https://www.nytimes.com/2010/01/10/magazine/10psyche-t.html (accessed Dec. 2020).

87 Corrigan, P. W., and Watson, A. C. (2002), ‘Understanding the impact of stigma on people with mental illness. World psychiatry: official journal of the World Psychiatric Association (WPA), 1(1): 16–20.

88 Kvaalea, Erlend P., et al. (2013), ‘Biogenetic explanations and stigma: A meta-analytic review of

associations among laypeople’, Social Science & Medicine 96:95–103, https://doi.org/10.1016/j.socscimed.2013.07.017. Mehta, S.and Farina, A. (1997), ‘Is being “sick” really better? Effect of the disease view of mental disorder on stigma’, Journal of Social and Clinical Psychology

Kvaalea, Erlend P., et al. (2013), ‘The “side effects” of medicalization: A meta-analytic review of how biogenetic explanations affect stigma’, Clinical Psychology Review 33 (6):782–94.

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